BPB MEDICA

Mirandola,  Modena 
Italy
https://www.biopsybell.com/


Welcome to NASS! We are waiting for you at booth n. 2233

BPB MEDICA™ is an Italian biomedical manufacturing company specializing in the design, production, and marketing of high-quality healthcare products for medical use and medical surgery devices in minimally invasive surgery. Today, BPB MEDICA™ has leveraged its 50 years of experience in the biomedical sector to develop new innovative product lines, growing the company on an international level and serving more than 70 countries in the world.

Brands: RENOVA SPINE™; DISKOM™; VERTEBROSTEEL™; VERTEBROPLASTIC™; BONE CEMENT; CEMIX™; EASYNJECT™; VERTEBRAL BIOPSY DEVICES; BONESTEM™; BONE ACCESS NEEDLE; SCREWFIX™;


 Press Releases

  • The burden of vertebral fractures
    The progressive ageing of the population has made the need for rapid, minimally invasive interventions increasingly central. For elderly patients, avoiding prolonged and high-risk periods of bed rest is not only a clinical choice but a vital priority.

    Within this context, two key procedures for treating vertebral fractures have gained widespread acceptance in recent years: vertebroplasty and kyphoplasty.

    Vertebral compression fractures (VCFs), often associated with osteoporosis, are not merely a source of acute pain; they represent a direct threat to patient independence.

    At Biopsybell, we are well aware that each day of immobilisation increases the risk of secondary complications. These are not only physical in nature, but also psychological: the sense of helplessness and isolation linked to prolonged bed rest may contribute to a rapid cognitive decline and a reduction in emotional well-being.

    Fortunately, interventional medicine today offers effective, targeted and clinically established solutions.

    Vertebroplasty vs kyphoplasty: what are the differences?
    It is essential to clearly understand the technologies available to the surgeon:

    • Vertebroplasty

    This procedure involves the percutaneous injection of bone cement (PMMA) into the fractured vertebral body, with the aim of stabilising the vertebra and reducing pain.
     

    • Kyphoplasty

    This technique involves the insertion of a balloon, which, once inflated, aims to partially restore vertebral height before the infusion of bone cement.


    The benefits of the minimally invasive approach
    Why should a patient opt for these procedures instead of conservative treatment based on bracing and prolonged rest?

    • Rapid pain relief

    Most patients experience significant pain reduction within the first 24–48 hours.

    • Return to daily activities

    Restoring mobility helps prevent pressure ulcers and muscle mass loss and contributes to preserving psychological well-being, reducing the emotional impact associated with loss of independence.

    • Day Hospital procedure

    Often performed under local anaesthesia or light sedation, these techniques minimise surgical stress and support a faster recovery.


    Safety first: the excellence of Biopsybell materials
    The success of a vertebral stabilisation procedure is closely linked to the quality of the instrumentation used. Biopsybell kits are designed to provide clinicians with excellent ergonomics and precise control over injection pressure. In addition, our bone cement ensures optimal viscosity and radiopacity, technical parameters that translate into a high level of safety for both surgeon and patient.

    Conclusion
    Chronic pain and immobility no longer need to be accepted as inevitable consequences of ageing. The synergy between minimally invasive surgery and high-precision medical devices makes the return to an active life a tangible goal. Restoring movement ultimately means restoring dignity, autonomy and quality of life for our elderly patients.

  • At BPB MEDICA™, we embrace the evolution of minimally invasive medicine, developing smart solutions that reduce trauma and improve clinical outcomes.


    In recent years, medicine has taken significant steps toward increasingly less invasive approaches. Where once complex surgical procedures and long hospital stays were required, today many conditions can be treated with minimally invasive techniques that offer tangible benefits for both patients and healthcare systems.

    The principle is simple: minimise tissue trauma while ensuring maximum therapeutic effectiveness. This translates to a faster recovery, fewer postoperative complications, and a quicker return to everyday life. Unsurprisingly, the demand for minimally invasive solutions is constantly growing and represents one of the most solid trends in modern clinical practice.

    Fields such as diagnostics (through increasingly precise biopsy procedures), spinal surgery, and regenerative medicine are among those most affected by this transformation. Carefully designed instruments play a decisive role in making these techniques not only possible but also safe and reliable.

    For physicians, relying on minimally invasive devices means offering patients effective treatments that are less traumatic and deliver better outcomes.
    For patients, it means approaching procedures with less fear and returning to their daily lives more quickly.

    Minimally invasive medicine is therefore not just a trend, but a true clinical philosophy that places the quality of care and patient well-being at its core.

    In this context, BPB MEDICA™ supports physicians and healthcare professionals with devices designed to reduce trauma, increase precision, and improve clinical outcomes:

    • spinal surgery tools such as DISKOM™, a device for percutaneous discectomy, RENOVA SPINE™, instruments for kyphoplasty, and the complete line for vertebroplasty;
    • a range of needles for bone and soft tissue biopsy, designed to minimise damage to surrounding tissues;
    • regenerative medicine solutions such as LIPO-STEM DUO™ and MARROW-STEM™, dedicated to the collection of mesenchymal cells;
    • oocyte aspiration and prenatal diagnosis needles, developed to ensure maximum delicacy and safety.
       

    Our continuous research and development confirm a clear mission: to deliver reliable and innovative technologies that transform daily practice into real benefits for patients.

  • Discover the clinically validated performance of MARROW-STEM™, BPB MEDICA™'s device for selective bone marrow aspiration. Designed to maximise mesenchymal stem cell (MSC) yield, it offers a sterile, efficient and contamination-free alternative to centrifugation-based systems.


    At BPB MEDICA™, we believe in evidence—not assumptions. That’s why the performance of our MARROW-STEM™ device was rigorously validated under the standards of EU Regulation 2017/745, ensuring both safety and clinical efficacy.

    A Closer Look at the Validation Process:
    To evaluate the device’s ability to efficiently harvest mesenchymal stem cells (MSCs), we conducted flow cytometric analysis on bone marrow samples taken from orthopaedic patients with preserved hematopoietic profiles.

    Key steps included:
    • Treating marrow samples to lyse red blood cells and isolate the nucleated cell fraction.
    • Using a precise antibody mix to identify the non-hematopoietic stromal fraction containing MSCs.
    • Quantifying the MSC population via fluorescence-activated cell sorting (FACS).

    Results That Speak for Themselves:
    • 98% cell viability in the collected samples.
    • ~0.093% of cells were confirmed to be MSCs—remarkable, considering these cells typically represent only 0.001–0.1% of bone marrow mononuclear cells.
    • High reproducibility and consistent performance across samples.

    The Added Value of Selective Aspiration:
    Compared to traditional centrifuge-based systems (internal benchmark data):
    • MARROW-STEM™ delivered over twice the concentration of colony-forming MSCs (CFU-f) per ml.
    • Peripheral blood contamination was significantly lower.
    • The entire procedure is performed within a sterile field, reducing infection risks and avoiding the loss of valuable biological material.

    Conclusion:
    This validation confirms what our engineers designed MARROW-STEM™ to do: maximise MSC yield with minimal invasiveness, while improving sterility and preserving ease of use. The device not only performs reliably but also represents a smarter, cleaner, and more efficient alternative to centrifugation-based bone marrow harvesting.


 Featured Products

  • DISKOM™ - Percutaneous discectomy device

    DISKOM™ is a high-performance percutaneous discectomy system designed to reduce pressure on nerve roots and surrounding tissues. By removing disc herniation through a minimally invasive procedure, DISKOM™ ensures effective results with minimal patient trauma.

    ...

  • RENOVA SPINE™

    RENOVA SPINE™ is a minimally invasive system for kyphoplasty procedures to treat fractures, restore vertebral body height and reduce back pain.

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  • VERTEBROPLASTY NEEDLES

    VERTEBROSTEEL™ (with steel handle) and VERTEBROPLASTIC™ (with plastic handle) are intended to be used in vertebroplasty procedures to inject cement into the vertebral body. 

    ...


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