NanoBone® Bone Graft, A New Dimension in Bone Repair.

NanoBone Bone Graft harnesses the body’s capacity to heal bone and is an effective standalone grafting material. NanoBone consists of nanocrystals of hydroxyapatite, bioidentical to human bone, in a silica gel matrix. Upon implantation, NanoBone triggers angiogenesis, enhancing the differentiation of bone forming cells and stimulating new bone formation. It is highly nanoporous, providing 40X greater surface area for binding autologous growth factors including BMP-2 critical to new bone formation. In 10-15 days, NanoBone is replaced by an autologous osteogenic matrix and the normal process of cell-mediated bone formation and resorption proceeds until completely converted to autologous bone. 

NanoBone has been used successfully for more than fifteen years in Europe and the US in more than 100,000 clinical cases. In a prospective study, bone healing with NanoBone Bone Graft used alone was comparable to autograft with a lower complication rate. This is the same standard that growth factor products use to secure FDA approval and is in contrast to cellular allografts which are not required to demonstrate equivalency to autograft. 

Brands: Artoss, NanoBone, SBX Putty, QD, bone graft substitute, bone void filler


NanoBone Mechanism of Action

 Press Releases

  • Artoss, Inc. is pleased to announce that it achieved record sales of NanoBone Bone Graft products in the third quarter of 2020.

    Paul Byerley, Chief Executive Officer of Artoss, Inc., the exclusive North American distributors for NanoBone, said, “Through perseverance and diligent effort by our sales management and independent distributors, we accomplished record sales for the quarter. Our team’s continued hard work allowed us to achieve this milestone in the middle of a global pandemic. We are especially gratified to see new surgeon users and hospitals embrace the outstanding clinical outcomes and cost savings when using NanoBone as a standalone bone graft substitute.”

    NanoBone Bone Graft harnesses the body’s inherent capacity to heal bone. FDA has cleared NanoBone for use as a standalone graft, including in spinal fusion, for its ability to create an osteogenic environment that replicates the architecture and chemistry found in natural bone. NanoBone products have been used in Europe and the US for more than fifteen years in more than 100,000 clinical cases across all indications. They have been available in the United States through Artoss, Inc. since 2015.

    For further information, please contact:

    Artoss, Inc.
    425 E Saint Germain St., Suite 106
    Saint Cloud, MN 56304

 Featured Products

  • NanoBone® QD
    To extend the usability of NanoBone, we put the perfect handling of NanoBone SBX Putty in an applicator designed for QD – quick delivery....

  • NanoBone SBX Putty contains NanoBone granules in a ready-to-use formulation that has excellent handling properties. It is preferred by surgeons for its ease of use.

    To further extend the usability of NanoBone, we put the perfect handling of NanoBone SBX Putty in an applicator designed for QD – quick delivery. This easy-to-use device facilitates rapid implantation of our advanced bone graft in a controlled and precise manner. Artoss developed NanoBone QD to provide these benefits in a cost-effective delivery system. Available in 5ml and 10ml sizes.

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